Hi MurderMunkey
I think it will be more natural to a Trad group than most Indie games. Don Corcoran certainly thinks so. See <a href="http://www.story-games.com/forums/comments.php?DiscussionID=7835" target="_blank">Don's post</a> where he says...
<blockquote>"<i>My estimation was that 3:16 is an excellent traditional RPG more so than a weak Story Game. As a traditional game it has all the GMiness and task resolution with some fantastic narrative elements. Let me expand on that. This game has a lot of great advice for roleplaying and storytelling. It really is what many traditional RPGs should be: Lets get to the point and play.</i>"</blockquote>
I also think that an Indie group will love it too, but its appeal is that the buy-in is very low and the play is very natural. I put advice in the book that I would have wanted as a player when I was starting out gaming all those years ago.