That said....one of my favorite "that time the players derailed the entire campaign in the first session..." stories is because the martial artist-optimized character rolled 8-9, and his target fumbled. And the other guy ate an Overkill result.
Which would have been cool, if the guy wasn't a no-name incidental security guy manning the nightclubs back office. All because they wanted to turn off the security cameras while they met the Johnson for the Job. But it sort of escalated from there, up to and including a declaration of "no witnesses" and sneaking into the hospital to take care of the other surviving guard (who got KOd with a taser).
Yeah, fun times.